How do you pronounce "enzyme"?

In American English: /ˈɛnˌzaɪm/ (EHN-zeyem). In British English: /ˈɛnzˌaɪm/ (EHNZ-eyem). In Canadian English: /ˈɛnˌzaɪm/ (EHN-zeyem). In Australian English: /ˈɛnzaɪm/ (EHNZ-eyem).

Is "enzyme" pronounced differently in American and British English?

Yes. In American English it's pronounced /ˈɛnˌzaɪm/ (EHN-zeyem), while in British English it's /ˈɛnzˌaɪm/ (EHNZ-eyem).

How to Pronounce "enzyme"

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enzyme

/ˈɛnˌzaɪm/

EHN-zeyem

Syllable Breakdown

ɛnen·zaɪmzyme

Source

90%confidence📘 CMU Pronouncing Dictionary v0.7b

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Last updated: 2026-02-14