How do you pronounce "nucleotide"?

In American English: /ˈnuːkliːəˌtaɪd/ (NOOKL-ee-uh-teyed). In British English: /njˈuːklɪˌɒtaɪd/ (NY-ookl-i-ot). In Canadian English: /ˈnuːkliːəˌtaɪd/ (NOOKL-ee-uh-teyed). In Australian English: /njˈuːklɪˌɒtaɪd/ (NY-ookl-i-ot).

Is "nucleotide" pronounced differently in American and British English?

Yes. In American English it's pronounced /ˈnuːkliːəˌtaɪd/ (NOOKL-ee-uh-teyed), while in British English it's /njˈuːklɪˌɒtaɪd/ (NY-ookl-i-ot).

How to Pronounce "nucleotide"

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nucleotide

regional

/ˈnuːkliːəˌtaɪd/

NOOKL-ee-uh-teyed

Syllable Breakdown

nuːklnu·iːcl·əeo·taɪdtide

Source

80%confidence📘 CMU Pronouncing Dictionary v0.7b

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Last updated: 2026-02-14